Alexander Fleming was a Scottish microbiologist and physician. He is credited with discovering penicillin, the world's first effective antibiotic substance; a discovery that changed the course of history. He also discovered lysozyme, an antimicrobial enzyme which forms part of the innate immune system. In 1999, Fleming was named in Time magazine's 100 Most Important People of the 20th century list.
A pioneer of psychedelic drug synthesis, Alexander Shulgin came to be known as The Godfather of Ecstasy, for reinventing the drug MDMA, or ecstasy, for medical use. The Harvard drop-out, who later studied psychiatry and pharmacology, would often experiment his newly invented drugs on himself, his wife, and his friends.
As part of the FDA, Frances Oldham Kelsey prevented thalidomide from being allowed in the US drug market as a painkiller, as she was unsure of its impact. Her concerns were proved right when the drug caused birth defects in European children. She was subsequently awarded by the US president.
Howard Florey was an Australian pathologist and pharmacologist. He is best remembered for his role in the formation of penicillin, for which he shared the prestigious Nobel Prize in Physiology or Medicine with Alexander Fleming and Ernst Chain in the year 1945. Florey is credited with carrying out the first clinical trial of penicillin at the Radcliffe Infirmary in 1941.
The daughter of Jewish immigrants in New York, Gertrude B. Elion excelled in chemistry at Hunter College, where she studied for free, but was initially unable to find a job due to gender bias. The renowned biochemist and pharmacologist later won a Nobel and became a pioneer in medical research.
11 Ferid Murad
Sir James W. Black was a Scottish pharmacologist and physician. Black, who became interested in the study of the human heart and its reaction to adrenaline, developed a beta-blocker named propranolol to treat heart diseases. He is also credited with developing cimetidine, a drug used to cure stomach ulcers. He was honored with the 1988 Nobel Prize for Medicine.
15 Li Shizhen
Salvador Moncada is a Honduran-British pharmacologist and professor. He is well known for his discoveries related to nitric oxide function and metabolism. In the past, he was the research director of the Wellcome Research Laboratories and is currently the research domain director for cancer at the University of Manchester. He is married to Princess Marie-Esméralda of Belgium.
Czech-American biochemist Carl Ferdinand Cori’s interest in science was not surprising, with him being a zoologist’s son. Along with his wife, Gerty Cori, and Argentine physiologist Bernardo Houssay, Cori won the Nobel Prize for finding out that glycogen is an energy storehouse of the body.
American pharmacologist and Nobel laureate Alfred G. Gilman is best remembered for his research on G proteins. Born to a Yale pharmacology professor and author father, he was destined to make it big in science. He also taught at the University of Virginia and other institutes and co-established a biotechnology company.
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25 Daniel Bovet
Earl W. Sutherland Jr. was a pharmacologist and biochemist known for his work in the field of hormones. He was honored with a Nobel Prize in Physiology or Medicine in 1971. As a young man, he worked in the laboratory of Nobel laureate Carl Ferdinand Cori. Under Cori’s guidance, he began his research on the effects of hormones.