49 Years Old Females

Actress Kate Winslet’s most enduring character remains that of the protagonist in the 1997 blockbuster film Titanic, which made her an international star. She’s also known for doing period roles in films like Sense and Sensibility, Jude and Hamlet. Some of her other notable films are Iris, Little Children, Steve Jobs and The Reader. She won an Oscar for her performance in The Reader. 

Charlize Theron is a former model and was an aspiring ballerina whose career came to a halt after a knee injury. However, an unexpected encounter brought her in the world of acting and she went on achieve tremendous success including winning an Academy Award and a Golden Globe Award. She is currently one of the world's highest-paid actresses.

Australian actress Isla Fisher attained widespread fame in 2005 when she starred in the commercially successful Hollywood film Wedding Crashers. Some of her other notable films are The Great Gatsby, Now You See Me, I Heart Huckabees, Bachelorette, Rango and Rise of the Guardians. She has also acted in television series and is an author of children’s books.

The quintessential action heroine of Hollywood, Milla Jovovich was rightly called the reigning queen of kick-butt by VH1 in 2006. Milla Jovovich is synonymous with the Resident Evil film series as the series revolves around its central character Alice, played by Milla. The Resident Evil film franchise is the highest-grossing movie series to be adapted from video games.

An actress, director, writer, and producer, Rashida Jones is a multi-talented woman who first gained prominence as a TV actress. A Harvard University graduate, the bright young woman entered the entertainment industry in the mid-1990s and has since made a name for herself. She is the recipient of several awards including a Grammy.

Emmanuelle Chriqui is a Canadian model and actress. She is known for portraying important roles in films like You Don't Mess with the Zohan. Also known for her good looks, Emmanuelle Chriqui was voted the Most Desirable Women of 2010 in a poll conducted by a free online men's web portal called AskMen.

Judy Greer is an American actress and director who established herself in the film industry through sheer hard work and determination. A self-made woman, Judy Greer has received several honors for her work in films and TV. Judy Greer is also credited with popularizing meditation, especially Transcendental Meditation.

Candace Cameron Bure is an American actress best known for bringing the popular fictional character, Aurora Teagarden, to life with her impressive performance in the film adaptation of the crime novel series based on Aurora Teagarden. Also known for her dancing skills, she finished third in the 18th season of the popular dancing TV reality series Dancing with the Stars.

Mexican American actor, singer, and songwriter Sara Ramirez is the recipient of several awards, including a Tony Award. Born in Mexico, they moved to America as a child. They became interested in acting in their teens and acted in school plays before taking up roles in theater plays. Soon, they ventured into TV and films as well.

American actress, Keri Russell, is best known for playing the titular character in teen drama Felicity and a KGB agent in thriller series The Americans. The Golden Globe Award winning actress made her debut as a teenager and later transitioned into playing more mature roles in films, television and stage. Her notable films include Mission: Impossible III, Waitress and Bedtime Stories.

Paula Patton is an American actress best known for her portrayal of Jane Carter in the 2011 film Mission: Impossible – Ghost Protocol. She is also famous for playing Ms.Blu Rain in the 2009 American drama film Precious, for which she was honored at the Boston Society of Film Critics Award. 

Amy Smart is an American actress who has played important roles in films like Varsity Blues, Road Trip, Rat Race, and The Butterfly Effect. After starting her career as a fashion model in Italy, Smart enrolled in acting school and went on to become a successful actress. She serves as an inspiration to those models who aspire to become actresses.

Australian singer-songwriter, voice-actress and director Sia Furler rose to fame with albums like We Are Born. Moving on, she bolstered her career with albums like 1000 Forms of Fear that debuted atop the U.S. Billboard 200 chart and singles like Cheap Thrills, her first Billboard Hot 100 number-one. Furler has also co-written hit songs like Diamonds, Titanium and Wild Ones.

Kaitlin Olson is an actress and comedian. She started her career with the improvisational group The Groundlings and went on to become one of the most popular members of the group. She then established herself in the American TV industry, landing critical roles in series like Flipped. After marrying Rob McElhenney, Olson bought Skinner's Bar, which was renamed Mac's Tavern.

Kelly Macdonald is a Scottish actress known for playing Diane Coulston in the 1996 black comedy-drama film, Trainspotting. Kelly Macdonald received critical appreciation for portraying Gina in the made-for-television drama film, The Girl in the Café, for which she won the Primetime Emmy Award. Eastwood High School, where she studied, has a theatre and drama studio named in her honor.

Shu Qi is a Taiwanese-Hong Kong model and actress best known for playing Nie Yinniang in the critically acclaimed 2015 film, The Assassin, for which she received the prestigious Asian Film Award. Starting from 2013, Shu Qi was named in three successive Forbes China Celebrity 100 lists. She is also one of the highest-paid Taiwanese-Hong Kong actresses.

Tara Reid is best known as Vicky from the American Pie movies and Bunny Lebowski from The Big Lebowski. Fans also loved her as April in the TV film Sharknado and its sequels. She appeared in her own travel show, Taradise, and in the eighth season of Celebrity Big Brother.

Kellie Martin is an American actress known for playing important roles in popular TV series, such as Life Goes On and ER. For her portrayal of Rebecca Thacher in Life Goes On, Kellie Martin won two Young Artist Awards. Kellie Martin is also famous for voicing Daphne Blake in the animated mystery comedy series, A Pup Named Scooby-Doo.

Part of the iconic British all-girl pop band of the 1990s, Spice Girls, Emma Bunton was nicknamed Baby Spice, for being the youngest in the group. Known for her signature pigtails and bright blue eyes, she later went solo and also appeared in the BBC One series Absolutely Fabulous.

Erin Burnett is an American news anchor. Dubbed the International Superstar, Burnett has hosted her own show Erin Burnett OutFront from the borders of Afghanistan, Israel, and the United Arab Emirates; she has also worked on a number of documentaries filmed inside India, Nigeria, Russia, and Libya. She has also reported from countries like Pakistan and China.

Sally Hawkins is a prominent English actress who has been nominated for two Academy Awards and five British Independent Film Awards. She graduated from the Royal Academy of Dramatic Art and began her career as a stage actress and became immensely successful. She eventually ventured into films as well and acted in numerous hit films. 

Canadian fitness model and former wrestler Trish Stratus is known for her stint with WWF (later renamed WWE). The Diva of the Decade and three-time WWE Babe of the Year has also been a WWE Hardcore Champion. She also became the first female to earn the Lou Thesz Award.

Marsha Thomason is an English actress best known for portraying Sarah Evers in the 2003 American film, The Haunted Mansion. She took an interest in acting at the age of 13 when she started taking part in youth theatre productions at the Oldham Theatre Workshop. She then went on to establish herself as an actress in the American TV industry.

Cynthia Daniel is a photographer and former actress. The twin sister of Brittany Daniel, Cynthia followed in the footsteps of her sister to become an actress. However, she retired from acting in 1997 and chose to become a photographer, even as her twin sister Brittany Daniel continued to pursue acting.

Annie Parisse is an American actress known for her portrayal of Julia Snyder in the TV soap opera As the World Turns, for which she received a Daytime Emmy Award nomination under the Outstanding Younger Actress in a Drama Series category. Parisse is also known for playing important roles in TV series like Law & Order and Friends from College.

A versatile actress and avid animal activist, Emmanuelle Vaugier has been busy both on television and in films since her debut in 1995. Since then she has been appearing in scores of productions, winning awards for her roles in films like Susie's Hope and It's Christmas, Carol!, concurrently running The Fluffball Foundation,  a charitable organization that rescues animals across USA.