66 Years Old Females

Michelle Pfeiffer is one of those rare Hollywood actresses who delivers Oscar-worthy performances every time she faces a camera. In her nearly half-a-century long career, there’s hardly a genre Pfeiffer hasn’t explored and conquered. Showering us with charm and unmatched talent in comedies, dramas, romance, and thrillers, this Golden Globe winner is one of the best actresses of this era.

Sharon Stone is an American actress who is best known for her performance in the erotic thriller Basic Instinct in 1992. The film gave her the tag of sex symbol. Thereafter, she went on to do notable films like Casino, The Muse, The Mighty, The Last Dance and Alpha Dog. By 2010s, she gravitated towards the small screen.

Fran Drescher is an American actress and comedian. Characterized by her thick New York accent and nasal voice, Fran Drescher serves as an inspiration to many cancer patients as she successfully fought off the disease after suffering from uterine cancer. She is also an outspoken LGBT rights activist and healthcare advocate.

Holly Hunter established herself as an actress in the American film industry after being born into a middle-class household, proving to the world that talent and hard work can make dreams come true. She also serves as an inspiration to those suffering from partial hearing loss as she has achieved popularity despite her inability to hear with her left ear.

Melanie Griffith was a successful and popular Hollywood actress in the 1980s and the 1990s. Body Double, Buffalo Girls, Pacific Heights, Mulholland Falls, Lolita and The Bonfire of the Vanities are some of her notable films. She has also worked in several television series, mainly in the 2000s when her movie career waned. She had issues with alcohol and drug addiction.

Caroline Kennedy is an American author, diplomat, and attorney. The only surviving child of John F. Kennedy and Jacqueline Bouvier Kennedy, Caroline served as the US Ambassador to Japan between 2013 and 2017. A prolific author who writes about civil liberties, Caroline Kennedy has also served as a spokesperson for the Kennedy family's legacy.

Former actress Linda Kozlowski made her debut as a stage actress and eventually ventured into films. She gained international popularity with her role in the Australian film Crocodile Dundee, during the filming of which she also met her future husband. She retired in the early 2000s after a career spanning two decades.

Nana Visitor is an American actress well-known for portraying important roles in popular TV series, such as Star Trek: Deep Space Nine and Wildfire. Thanks to her popularity and association with the Star Trek series, an amateur astronomer named William Kwong Yu Yeung honored her by naming the asteroid 26733 Nanavisitor after her in 2001.

English-born Australian actress, director, and screenwriter, Rachel Ward, has been active in the entertainment industry for over 40 years. She attended the Byam Shaw School of Art in London for some time but quit midway to start her career as a model. Following a successful stint as a model, she began acting and screenwriting.

Denise Crosby is an American model and actress best known for playing Tasha Yar in the popular sci-fi TV series Star Trek: The Next Generation. Before establishing herself as a prominent actress, Denise Crosby worked as a model and turned heads when she posed nude for one of the issues of Playboy magazine in 1979.

Lori Singer is an American actress, model, and cellist. A musical prodigy, Singer made her debut as a cellist at the age of 13. She then became the Juilliard School's youngest graduate before shifting her attention towards acting. In 1982, Lori Singer won the ShoWest Newcomer of the Year Award for playing Jodi Belcher in the TV film Born Beautiful.

Dinah Manoff is an American actress best known for playing Libby Tucker in the comedy-drama play I Ought to Be in Pictures, which earned her a Tony Award. The daughter of actress Lee Grant, Manoff followed in the footsteps of her mother to establish herself as an actress and television director.

Jane Wiedlin is an American singer-songwriter, musician, and actress. She achieved popularity as the backing vocalist and rhythm guitarist of the popular band The Go-Go's. Jane Wiedlin is also an ardent animal rights activist; she works closely with organizations, such as PETA. An openly bisexual musician, Jane Wiedlin serves as an inspiration to the LGBT community.

Kate Burton is an American actress best known for her portrayal of Ellis Grey in the popular medical drama television series, Grey's Anatomy. The daughter of famous actors, Sybil Christopher and Richard Burton, Kate is also renowned for her stage work and has received three Tony Award nominations so far. 

Michaëlle Jean is a Canadian stateswoman who became the first black person and Haitian Canadian to serve as Governor General of Canada, a position which she held from 2005 to 2010. In 2015, Jean became the first woman to serve as the secretary-general of the International Organisation of La Francophonie, a position which she held until the end of 2018.

Slavica Ecclestone is a Croatian model best known for her association with Armani during her early career. She achieved international recognition after marrying British business magnate Bernie Ecclestone, who is 28 years older than Slavica. They married despite many differences, including a difference in height and language barrier, which attracted the attention of the media all over the world.