Comedian, television host and actress Ellen DeGeneres is the first actress to win a Saturn Award for a voice performance, winning the accolade for her role in the film Finding Nemo. She has hosted the Academy Awards and has published four books. She is openly lesbian and supports LGBTQA+ rights. She has been accused of workplace harassment.
4 Lucy Liu
American actress, Lucy Liu, shot to fame with television series Ally McBeal and later proved her acting skills with films like Charlie's Angels, Kill Bill, Volume 1, Shanghai Noon and television series Elementary and Southland. Intelligent and multitalented, she has voiced animated films, turned producer/director, made her Broadway debut and last but not the least, is also a visual artist.
The youngest of the popular Workman siblings, Ariel Winter Workman has established herself as a successful actress after starting her career as a child star. She has also contributed immensely as a voice actress in films and video games.
Fran Drescher is an American actress and comedian. Characterized by her thick New York accent and nasal voice, Fran Drescher serves as an inspiration to many cancer patients as she successfully fought off the disease after suffering from uterine cancer. She is also an outspoken LGBT rights activist and healthcare advocate.
Adrianne Palicki is an American actress known for playing important roles in TV series like Friday Night Lights and Agents of S.H.I.E.L.D. Adrianne Palicki went on to establish herself as a respectable actress despite suffering from celiac disease.
Kathie Lee Gifford achieved celebrity status by working as a television presenter. She then became a singer-songwriter and author, cementing her place in the entertainment industry. Also known for her charity work, Kathie serves as an ambassador for Childhelp, a non-profit organization working towards preventing child abuse.
12 Alicia Witt
Sherilyn Fenn is an American actress best known for playing Audrey Horne on the mystery horror drama TV series, Twin Peaks. Over the years, Fenn's acting skills have been overshadowed by her good looks with several publications including her on their lists like the most beautiful women in the world, sexiest women in the world, and 50 hottest babes ever.
15 Rosa Salazar
16 Grey DeLisle
Virginia Madsen is an American actress. Over the years, Madsen has contributed to the success of several films and TV series, such as Fire with Fire, Modern Girls, Moonlighting, and American Dreams. She is also credited with establishing Title IX Productions, a film production company which she started in 2008.
18 Laura Bailey
19 Nasim Pedrad
20 Sela Ward
Sela Ann Ward is best known for her Emmy-winning role of Teddy Reed in Sisters. She won another Emmy and a Golden Globe for playing Lily Manning in Once and Again. Fans also loved her in the series House and CSI: NY, and the movie The Day After Tomorrow.
21 Pamela Adlon
23 Mena Suvari
24 Uzo Aduba
25 Carey Lowell
Carey Lowell is an American actress best known for playing Bond girl Pam Bouvier in the 1989 James Bond film Licence to Kill. From 2014 to 2016, Carey Lowell was involved in highly contested divorce proceedings after separating from actor Richard Gere whom she had married in 2002.
26 Eva Gabor
Kristy McNichol is a retired American comedian, singer, and actress. After being born into a middle-class family, McNichol started acting at a young age and went on to become one of the most popular teen stars of her generation. After her retirement, Kristy McNichol devoted her time to charity work and taught acting in Los Angeles.
28 Loretta Swit
Loretta Swit is a veteran American stage and small screen actress who became a household name with her award-winning portrayal of Major Margaret ‘Hot Lips’ Houlihan in M*A*S*H, a comedy-drama series on CBS television. Apart from playing a wide range of character roles on television and stage, she also appeared in movies and hosted a documentary on the Korean war.
30 Kate Micucci
33 Rhea Seehorn
A popular actress, producer, and activist, Rosario Dawson is known as much for her involvement in politics and philanthropy as for her work in films and television. A strong supporter of various charitable organizations, such as One Campaign and Parents, Families and Friends of Lesbians and Gays, Rosario came out as member of the LGBT community in 2020.
Willa Holland is an American model and actress known for playing important roles in TV series like Gossip Girl and Arrow. She started her career as a model, working for brands like Guess, Gap, and Ralph Lauren. She then went on to establish herself as an actress, winning the Boston International Film Festival Award for her performance in the movie Tiger Eyes.
39 Jillian Bell
40 Cree Summer
Phyllis Smith is an American actress best known for portraying Phyllis Vance in the popular mockumentary TV series, The Office, for which she received a couple of Screen Actors Guild Awards. Also known for her skills as a voice actress, Smith was honored with the prestigious Annie Award for voicing Sadness in the 2015 computer-animated comedy film, Inside Out.
44 Gina Carano
A former mixed martial artist, Gina Carano went on to become an actress; she uses her martial arts skills to perform stunts in popular action movies. Before becoming an actress, she was quite popular in the MMA scene, being termed the face of women's MMA. In 2008, she was named in a Top 10 Influential Women list.