Cartier was introduced to King Francis I by Jean le Veneur, bishop of Saint-Malo and abbot of Mont-Saint-Michel, in 1534. He was reasonably experienced in navigation by then and the king asked him to undertake the official exploration of North America.
The king commissioned him to "discover certain islands and lands where it is said that a great quantity of gold and other precious things are to be found", and Cartier set sail on April 20, 1534.
During this voyage he explored parts of Newfoundland and the Gulf of Saint Lawrence. He also encountered aboriginal people on the north side of Chaleur Bay and conducted some trade with them. He also captured two natives belong to the Saint Lawrence Iroquoian tribe and brought them to France in September 1534.
Cartier reported to the king all that he had discovered. The king was impressed with his findings and sent him on another expedition the following year. He set sail on his second voyage with three ships, 110 men, and his two Iroquoian captives to serve as guides.
The expedition navigated Saint Lawrence, travelled to as far as Quebec and established a base. Then Cartier sailed downriver to reach modern-day Montreal where he was welcomed by the Iroquois. From the natives he learned of some other rivers that led farther west, where gold, silver, copper and spices could be found.
Cartier and other voyagers planned to travel farther west in search of gold, silver and spice but before they could travel, winter set in. The winter was harsher than what they had expected and thus they had to stall their future plans for a while. Several of Cartier’s men succumbed to diseases during the winter and to make matters worse, the cordial relations between the explorers and the natives became strained.
When spring set in and the rivers began to melt, Cartier captured some of the Iroquois chiefs and sailed for France. Then he reported to the king what he had learned about the lands which abounded in riches farther in the interior of the lands they had explored.
War in France temporarily prevented the king from sending out any expeditions for a few years. With the political situation improving in France, the king ordered Jacques Cartier to return to Canada and start the colonization process. He departed on his third voyage with five ships in May 1541, with the aim of finding the "Kingdom of Saguenay" and its riches, and of establishing a permanent settlement along the Saint Lawrence River.
Cartier and his men reached Quebec and set up camp. There they found an abundance of what they thought were gold and diamonds. Cartier fervently collected what he believed to be treasures and abandoned the base and returned to France to sell the booty.
During this time, other colonists sent by the king were enroute to Canada and were supposed to join Cartier in establishing a settlement there. But Cartier did not wait for them and fled to France. Back in his homeland he got the biggest shock when he realized that the “diamonds” and “gold” he had so painstakingly collected were actually just worthless quartz crystals and iron pyrites, respectively.
Having lost favor with the king because of his irresponsible behavior, he was never sent on another commissioned voyage.