Fran Drescher is an American actress and comedian. Characterized by her thick New York accent and nasal voice, Fran Drescher serves as an inspiration to many cancer patients as she successfully fought off the disease after suffering from uterine cancer. She is also an outspoken LGBT rights activist and healthcare advocate.
10 Alicia Witt
11 Laura Bailey
Virginia Madsen is an American actress. Over the years, Madsen has contributed to the success of several films and TV series, such as Fire with Fire, Modern Girls, Moonlighting, and American Dreams. She is also credited with establishing Title IX Productions, a film production company which she started in 2008.
Emily Mortimer is an English-American screenwriter and actress. Mortimer, who started her acting career in stage productions, went on to establish herself as a bankable actress in the British film and TV industry. In 2010, she became an American citizen and has since been playing important roles in American films.
14 Lena Headey
15 Mena Suvari
A popular actress, producer, and activist, Rosario Dawson is known as much for her involvement in politics and philanthropy as for her work in films and television. A strong supporter of various charitable organizations, such as One Campaign and Parents, Families and Friends of Lesbians and Gays, Rosario came out as member of the LGBT community in 2020.
Sherilyn Fenn is an American actress best known for playing Audrey Horne on the mystery horror drama TV series, Twin Peaks. Over the years, Fenn's acting skills have been overshadowed by her good looks with several publications including her on their lists like the most beautiful women in the world, sexiest women in the world, and 50 hottest babes ever.
19 Nasim Pedrad
20 Pamela Adlon
Natalie Dormer is a popular English actress who received international recognition after playing Margaery Tyrell in one of the most popular TV series of all time, Game of Thrones. Also known for her charity work and advocacy, Natalie traveled to Tanzania in 2017 along with a humanitarian organization called Plan International to ban child marriage in the East African country.
23 Jenny Slate
25 Eva Gabor
29 Uzo Aduba
Kristy McNichol is a retired American comedian, singer, and actress. After being born into a middle-class family, McNichol started acting at a young age and went on to become one of the most popular teen stars of her generation. After her retirement, Kristy McNichol devoted her time to charity work and taught acting in Los Angeles.
31 Sela Ward
Sela Ann Ward is best known for her Emmy-winning role of Teddy Reed in Sisters. She won another Emmy and a Golden Globe for playing Lily Manning in Once and Again. Fans also loved her in the series House and CSI: NY, and the movie The Day After Tomorrow.
32 Rhea Seehorn
33 Loretta Swit
Loretta Swit is a veteran American stage and small screen actress who became a household name with her award-winning portrayal of Major Margaret ‘Hot Lips’ Houlihan in M*A*S*H, a comedy-drama series on CBS television. Apart from playing a wide range of character roles on television and stage, she also appeared in movies and hosted a documentary on the Korean war.
34 Kate Micucci
35 Carey Lowell
Carey Lowell is an American actress best known for playing Bond girl Pam Bouvier in the 1989 James Bond film Licence to Kill. From 2014 to 2016, Carey Lowell was involved in highly contested divorce proceedings after separating from actor Richard Gere whom she had married in 2002.
Willa Holland is an American model and actress known for playing important roles in TV series like Gossip Girl and Arrow. She started her career as a model, working for brands like Guess, Gap, and Ralph Lauren. She then went on to establish herself as an actress, winning the Boston International Film Festival Award for her performance in the movie Tiger Eyes.
38 Lucy Davis
40 Jillian Bell
41 Grey DeLisle
Brenda Blethyn is best known for her Golden Globe- and BAFTA-winning role in Secrets & Lies. She was also appreciated for her performances in the films Little Voice and Saving Grace, and the mini-series Anne Frank: The Whole Story. She has also performed on stage in Manchester.
Phyllis Smith is an American actress best known for portraying Phyllis Vance in the popular mockumentary TV series, The Office, for which she received a couple of Screen Actors Guild Awards. Also known for her skills as a voice actress, Smith was honored with the prestigious Annie Award for voicing Sadness in the 2015 computer-animated comedy film, Inside Out.
47 Janet McTeer
48 Cree Summer
Penelope Wilton is an English actress known for her work in theatre, film, and TV. The winner of several prestigious awards, such as the Olivier Award, Penelope Wilton was appointed an OBE for services to drama in the 2004 New Year Honours. In the 2016 Birthday Honours, she was elevated to become a DBE.