Famous American Pharmacologists

As part of the FDA, Frances Oldham Kelsey prevented thalidomide from being allowed in the US drug market as a painkiller, as she was unsure of its impact. Her concerns were proved right when the drug caused birth defects in European children. She was subsequently awarded by the US president.

John Pemberton was an American pharmacist best remembered for his invention of Coca-Cola. A Confederate States Army veteran, Pemberton suffered from a wound sustained during the Battle of Columbus. The injury led him to experiment with different kinds of toxins and painkillers, which in turn helped him invent the recipe to make Coca-Cola.

The daughter of Jewish immigrants in New York, Gertrude B. Elion excelled in chemistry at Hunter College, where she studied for free, but was initially unable to find a job due to gender bias. The renowned biochemist and pharmacologist later won a Nobel and became a pioneer in medical research.

Otto Loewi was a German-born American psycho-biologist and pharmacologist, whose research on neurology proved that chemicals were involved in the transmission of nerve impulses. Working with Sir Henry Dale, he established the role of acetylcholine as an endogenous neurotransmitter, co-winning the Nobel Prize for it. Later, he worked on diabetes and devised Loewi’s test for the detection of pancreatic disease.

Czech-American biochemist Carl Ferdinand Cori’s interest in science was not surprising, with him being a zoologist’s son. Along with his wife, Gerty Cori, and Argentine physiologist Bernardo Houssay, Cori won the Nobel Prize for finding out that glycogen is an energy storehouse of the body.

American pharmacologist and Nobel laureate Alfred G. Gilman is best remembered for his research on G proteins. Born to a Yale pharmacology professor and author father, he was destined to make it big in science. He also taught at the University of Virginia and other institutes and co-established a biotechnology company.

Earl W. Sutherland Jr. was a pharmacologist and biochemist known for his work in the field of hormones. He was honored with a Nobel Prize in Physiology or Medicine in 1971. As a young man, he worked in the laboratory of Nobel laureate Carl Ferdinand Cori. Under Cori’s guidance, he began his research on the effects of hormones.