![Joachim Frank Joachim Frank](http://www.thefamouspeople.com/profiles/thumbs/joachim-frank-55622-1.jpg)
Nobel Prize-winning German-American biophysicist Joachim Frank is best known for developing single-particle cryo-electron microscopy, or cryo-EM. He has been associated with Columbia University as a professor for a long time and is an Honorary Fellow of the Royal Microscopical Society. He has also helped ascertain the structure of ribosomes.